Argemone oil, sanguinarine, and epidemic-dropsy glaucoma.

نویسنده

  • S A HAKIM
چکیده

Argemone mexicana Linn. (Linnaeus, 1753; Tournefort, 1694), is a herb of the Papaveraceae (poppy family) indigenous to the West Indies (Fig. 1). The study of this herb and its active principles is important, first to circumvent the serious epidemics of dropsy and glaucoma resulting from the unintentional ingestion of its seed oil in tropical countries; secondly to find a method of producing in _ laboratoryanimals conditions similar to, if not identical with, glaucoma; and thirdly to examine the possibility that other simiilar pla-nts, by indirect ingestion, may play an insidious role in the causation of primary endemic

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Sanguinarine, Hydroxybutyrate Dehydrogenase and Fatigue in Epidemic Dropsy: A Retrospective Study of an Outbreak and its Control from Gujarat, India

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Epidemic dropsy is a clinical state resulting from use of edible oils adulterated with Argemone mexicana oil. Sanguinarine and dehydrosanguinarine are two major toxic alkaloids of Argemone oil, which cause widespread capillary dilatation, proliferation and increased capillary permeability. Leakage of the protein-rich plasma component into the extracellular compartment leads to the formation of ...

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عنوان ژورنال:
  • The British journal of ophthalmology

دوره 38 4  شماره 

صفحات  -

تاریخ انتشار 1954